Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-09T22:45:12.806Z Has data issue: false hasContentIssue false

Chapter 56 - Autologous Hematopoietic Cell Transplants for Autoimmune Diseases: Therapeutic Rationale and Limitations

from Section 15 - Hematopoietic Cell Transplants for Non-Neoplastic Diseases

Published online by Cambridge University Press:  24 May 2017

By
Marcelo C. Pasquini  and
Robert Peter Gale
Edited by
Hillard M. Lazarus ,
Robert Peter Gale ,
Armand Keating ,
Andrea Bacigalupo ,
Reinhold Munker  and
Kerry Atkinson
Edited in association with
Syed Ali Abutalib
Hillard M. Lazarus
Affiliation:
Case Western Reserve University, Ohio
Robert Peter Gale
Affiliation:
Imperial College London
Armand Keating
Affiliation:
University of Toronto
Andrea Bacigalupo
Affiliation:
Ospedale San Martino, Genoa
Reinhold Munker
Affiliation:
Louisiana State University, Shreveport
Kerry Atkinson
Affiliation:
University of Queensland
Syed Ali Abutalib
Affiliation:
Midwestern Regional Medical Center, Cancer Treatment Centers of America, Chicago
Get access
Type
Chapter
Information
Hematopoietic Cell Transplants
Concepts, Controversies and Future Directions
 , pp. 531 - 534
Publisher: Cambridge University Press
Print publication year: 2000

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Muraro, PA, Abrahamsson, SV. Resetting autoimmunity in the nervous system: The role of hematopoietic stem cell transplantation. Curr Opin Investig Drugs. 2010;11(11):1265–75.Google ScholarPubMed
Muraro, PA, Douek, DC, Packer, A, Chung, K, Guenaga, FJ, Cassiani-Ingoni, R, et al. Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients. J Exp Med. 2005;201(5):805–16.CrossRefGoogle ScholarPubMed
Arruda, LCM, Lorenzi, JCC, Sousa, APA, Zanette, DL, Palma, PVB, Panepucci, RA, et al. Autologous hematopoietic SCT normalizes miR-16, -155 and -142–3p expression in multiple sclerosis patients. Bone Marrow Transplant. 2015;50(3):380–9.CrossRefGoogle ScholarPubMed
Muraro, PA, Robins, H, Malhotra, S, Howell, M, Phippard, D, Desmarais, C, et al. T cell repertoire following autologous stem cell transplantation for multiple sclerosis. J Clin Invest. 2014;124(3):1168–72.CrossRefGoogle ScholarPubMed
Euler, HH, Marmont, AM, Bacigalupo, A, Fastenrath, S, Dreger, P, Hoffknecht, M, et al. Early recurrence or persistence of autoimmune diseases after unmanipulated autologous stem cell transplantation. Blood. 1996;88(9):3621–5.CrossRefGoogle ScholarPubMed
Burt, RK. BMT for severe autoimmune diseases: an idea whose time has come. Oncology (Williston Park). 1997;11(7):1001–14; 17, discussion 18–24.Google ScholarPubMed
Cooley, HM, Snowden, JA, Grigg, AP, Wicks, IP. Outcome of rheumatoid arthritis and psoriasis following autologous stem cell transplantation for hematologic malignancy. Arthritis Rheum. 1997;40(9):1712–5.CrossRefGoogle ScholarPubMed
Fassas, A, Anagnostopoulos, A, Kazis, A, Kapinas, K, Sakellari, I, Kimiskidis, V, et al. Peripheral blood stem cell transplantation in the treatment of progressive multiple sclerosis: first results of a pilot study. Bone Marrow Transplant. 1997;20(8):631–8.CrossRefGoogle ScholarPubMed
Marmont, AM, van Lint, MT, Gualandi, F, Bacigalupo, A. Autologous marrow stem cell transplantation for severe systemic lupus erythematosus of long duration. Lupus. 1997;6(6):545–8.CrossRefGoogle ScholarPubMed
Brodsky, RA, Petri, M, Smith, BD, Seifter, EJ, Spivak, JL, Styler, M, et al. Immunoablative high-dose cyclophosphamide without stem-cell rescue for refractory, severe autoimmune disease. Ann Intern Med. 1998;129(12):1031–5.CrossRefGoogle ScholarPubMed
Binks, M, Passweg, JR, Furst, D, McSweeney, P, Sullivan, K, Besenthal, C, et al. Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: procedure related mortality and impact on skin disease. Ann Rheum Dis. 2001;60(6):577–84.CrossRefGoogle ScholarPubMed
Burt, RK, Traynor, AE, Cohen, B, Karlin, KH, Davis, FA, Stefoski, D, et al. T cell-depleted autologous hematopoietic stem cell transplantation for multiple sclerosis: report on the first three patients. Bone Marrow Transplant. 1998;21(6):537–41.CrossRefGoogle ScholarPubMed
McSweeney, PA, Nash, RA, Sullivan, KM, Storek, J, Crofford, LJ, Dansey, R, et al. High-dose immunosuppressive therapy for severe systemic sclerosis: initial outcomes. Blood. 2002;100(5):1602–10.CrossRefGoogle ScholarPubMed
Farge, D, Labopin, M, Tyndall, A, Fassas, A, Mancardi, GL, Van Laar, J, et al. Autologous hematopoietic stem cell transplantation (HSCT) for autoimmune diseases: an observational study on 12 years of experience from the European Group for Blood and Marrow Transplantation (EBMT) Working Party on Autoimmune Diseases. Haematologica. 2009;95(2):284–92.Google Scholar
Pasquini, MC, Voltarelli, J, Atkins, HL, Hamerschlak, N, Zhong, X, Ahn, KW, et al. Transplantation for autoimmune diseases in north and South america: a report of the center for international blood and marrow transplant research. Biol Blood Marrow Transplant. 2012;18(10):1471–8.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×