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Chapter 109 - Causes of epilepsia partialis continua

from Section 5 - Status epilepticus

Published online by Cambridge University Press:  05 March 2012

By
Hirokazu Oguni  and
Frederick Andermann
Edited by
Simon D. Shorvon ,
Frederick Andermann  and
Renzo Guerrini
Simon D. Shorvon
Affiliation:
National Hospital for Neurology and Neurosurgery, London
Frederick Andermann
Affiliation:
Montreal Neurological Hospital and Institute
Renzo Guerrini
Affiliation:
Child Neurology Unit, Meyer Pediatric Hospital, Florence
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Summary

In the most recent ILAE-proposed Epilepsy Classification, epilepsia partialis continua (EPC) is classified into focal status epilepticus among continuous seizure types, and defined simply as a combination of focal seizures with continuous twitching in the same area correlated with Rasmussen syndrome, focal cerebral lesions of miscellaneous causes, or inborn errors of metabolism. EPC is most frequently encountered in chronic neurological conditions, for example Rasmussen syndrome, symptomatic focal epilepsy due to focal cortical dysplasia, and mitochondrial encephalopathy. EPC also occurs in patients with focal cortical dysplasia involving the sensorimotor cortex as well as in hemimegalencephaly. The epileptic seizures including EPC are generally resistant to antiepileptic drug (AED) therapy, but neurological deterioration is not evident except for that seizure-generated. Scanning with magnetic resonance imaging (MRI) can detect focal cortical dysplasia in the sensorimotor cortex with or without involvement of the adjacent cortex.
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The Causes of Epilepsy
Common and Uncommon Causes in Adults and Children
 , pp. 759 - 766
Publisher: Cambridge University Press
Print publication year: 2011

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