Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-26T17:59:00.376Z Has data issue: false hasContentIssue false

20 - Understanding cannabis use in schizophrenia

Published online by Cambridge University Press:  05 November 2011

By
David J. Kavanagh Leanne Hides  and
Kim T. Mueser
Edited by
David Castle ,
Robin M. Murray  and
Deepak Cyril D'Souza
David Castle
Affiliation:
University of Melbourne
Robin M. Murray
Affiliation:
Institute of Psychiatry
Deepak Cyril D'Souza
Affiliation:
Yale University, Connecticut
Get access

Summary

International surveys have found consistently high rates of cannabis use in schizophrenia. This chapter briefly reviews potential biological, personality and cognitive mechanisms underpinning the relationship between cannabis use and psychosis. A growing number of studies have examined motives and expectancies for cannabis use among individuals with psychosis. Quantitative studies using valid and reliable measures of motives and expectancies for substance use in psychosis report similar findings. A number of biological models have focused on the role of the endogenous cannabinoid system on neurodevelopment and brain functioning via activation of the dopamine and glutaminergic systems and suppression of gamma-aminobutyric acid (GABA) functions. The relationship between cannabis and psychosis is likely to involve a complex interaction between biological, psychological and environmental variables. Research has also highlighted the potential importance of genetic and biological factors, stress, coping style, negative effect as well as cannabis-use motives and expectancies.

Keywords

cannabinoidsCB1 receptorscerebellar-mediated behaviorschizophreniaPurkinje cellscerebellumendocannabinoid system
Type
Chapter
Information
Marijuana and Madness , pp. 218 - 224
Publisher: Cambridge University Press
Print publication year: 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×