Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-jkksz Total loading time: 0 Render date: 2024-12-26T15:15:31.399Z Has data issue: false hasContentIssue false

Chapter 5 - Cerebral microbleedmimics

from Section 1 - Historical aspects, detection and interpretation

Published online by Cambridge University Press:  05 July 2011

By
Neshika Samarasekera ,
Gillian Potter  and
Rustam Al-Shahi Salman
Edited by
David J. Werring
David J. Werring
Affiliation:
Institute of Neurology, London
Get access

Summary

The cerebral microbleed (CMB) mimics form two types: those that contain blood products and those that do not (resembling CMBs because of shared signal intensity and morphology on gradient-recalled echo (GRE) MRI). This chapter describes both types, and outlines how these can be differentiated from true CMBs. It suggests a topographical approach to the recognition of CMB mimics on brain imaging. The GRE sequences used in the detection of CMBs are sensitive not only to blood breakdown products (deoxyhemoglobin, methemoglobin, hemosiderin and ferritin) but also to other paramagnetic substances such as calcium, manganese and iron, all of which may appear as foci of low signal. In lobar regions of the brain, common CMB mimics include vascular flow voids and hypointensities arising from partial volume artefact. The development of susceptibility-weighted imaging (SWI) has improved the detection of structures containing extravascular blood products, as well as those containing venous deoxygenated blood.
Type
Chapter
Information
Cerebral Microbleeds
Pathophysiology to Clinical Practice
 , pp. 44 - 48
Publisher: Cambridge University Press
Print publication year: 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×