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9B - There Is a Role for Pre-conception Treatment with Vitamin D

Against

from Section II - IVF Add-ons

Published online by Cambridge University Press:  25 November 2021

By
Amit Shah
Edited by
Roy Homburg ,
Adam H. Balen  and
Robert F. Casper
Roy Homburg
Affiliation:
Homerton University Hospital, London
Adam H. Balen
Affiliation:
Leeds Centre for Reproductive Medicine
Robert F. Casper
Affiliation:
Mount Sinai Hospital, Toronto
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Summary

Whilst animal studies and some observational studies in humans have described an association between vitamin D and reproductive outcome, I do not believe that the evidence from prospect randomised studies is sufficient to recommend its routine use.

Type
Chapter
Information
50 Big Debates in Reproductive Medicine , pp. 49 - 50
Publisher: Cambridge University Press
Print publication year: 2021

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References

Bodnar, LM, Catov, JM, Simhan, HN, et al. Maternal vitamin D deficiency increases the risk of pre-eclampsia. J Clin Endocrinol Metab. 2007;92:3517–22.CrossRefGoogle Scholar
Kosta, K, Yavropoulou, MP, Anastasiou, O, Yovos, JG. Role of vitamin D treatment in glucose metabolism in polycystic ovary syndrome. Fertil Steril. 2009;92:1053–8.Google Scholar
Robinson, CJ, Wagner, CL, Hollis, BW, et al. Maternal vitamin D and fetal growth in early-onset severe pre-eclampsia. Am J Obstet Gynecol. 2011;204:566.CrossRefGoogle Scholar
Chu, J, Gallo, I, Tobias, A, et al. Vitamin D and assisted reproductive treatment outcome: a prospective cohort study. Reprod Health. 2019;16:106.CrossRefGoogle ScholarPubMed
RCOG. Vitamin D in pregnancy. Scientific Impact Paper No 43. June 2014. RCOG.Google Scholar

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