A study was conducted in 2004 to determine the effect of coapplication of the insecticides acephate, acetamiprid, bifenthrin, cyfluthrin, cypermethrin, dicrotophos, dimethoate, emanectin benzoate, imidacloprid, indoxacarb, lambda-cyhalothrin, methoxyfenozide, spinosad, thiamethoxam, and zeta-cypermethrin; the plant growth-regulator mepiquat pentaborate; a foliar sodium calcium borate micronutrient solution; and a foliar nitrogen fertilizer solution with glyphosate on the efficacy of weeds that commonly infest cotton. Barnyardgrass, hemp sesbania, johnsongrass, pitted morningglory, and sicklepod were grown in outdoor containers and treated with glyphosate at 1,120 g ai/ha alone or in coapplication at the three-to four- or seven-to eight-leaf growth stage. Glyphosate efficacy, based on visual control ratings at 7, 14, and 28 d after treatment (DAT) and fresh weight reduction of weed biomass at 28 DAT, was unaffected by chemical coapplication or application timing. Averaged across application timing and visual rating interval, glyphosate alone controlled barnyardgrass 97%, hemp sesbania 68%, johnsongrass 98%, pitted morningglory 68%, and sicklepod 89%. These results indicate that glyphosate coapplications evaluated offer producers the ability to combine pest and crop management strategies and reduce application costs without sacrificing control of weeds evaluated.