Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

1 results

  • Chapter 15 - Genetic interaction between circadian and homeostatic regulation of sleep

  • from Section 3 - Sleepphysiology and homeostasis
  • Edited by Paul Shaw, Mehdi Tafti, Michael J. Thorpy
  • Book:
    The Genetic Basis of Sleep and Sleep Disorders
    Published online:
    05 November 2013
    Print publication:
    24 October 2013, pp 147-161

  • Summary

    This chapter reviews the use of genetics in Drosophila to advance sleep research. Short-term memory can be evaluated in flies using an associative learning paradigm, aversive phototaxic suppression (APS). In 2008, the ventral lateral neurons (LNvs) were shown to promote wakefulness [44-46]. The LNvs are an extensively well-studied neuronal group that is a key part of the clock neurons network that controls circadian behaviors such as locomotor activity rhythms. Plasticity and memory consolidation only represent one of potential avenues for pursuing sleep function, many of the studies that have used Drosophila genetics to pursue functional questions focused on the relationship between sleep and plasticity. Along with the growing genetic toolbox it seems that the fly, in combination with human genetic studies, is uniquely poised to push our understanding of sleep mechanisms and function rapidly forward.