Field studies were conducted at two locations in Missouri in 1990 and 1991 to evaluate control of velvetleaf, ivyleaf morningglory, and cocklebur in soybean with label rates (1×) or reduced rates (0.5×) of four PPI herbicides followed with or without cultivation and POST application of one fourth (0.25×) the label rate of imazethapyr. Weed control and soybean yield with the 0.5× rate of preplant clomazone, imazaquin, metribuzin, and metribuzin + chlorimuron followed by either cultivation or imazethapyr POST was equivalent to a 1× rate of the PPI herbicides followed by either cultivation or imazethapyr. Weed control and soybean yield with the 0.5× rates of the PPI herbicides without cultivation or POST imazethapyr were lower than with 1× rates of PPI herbicides.