This paper argues that the mature form of the political doctrine of the Ayatollah Khomeini (1902–89), Iranian Shiite religious authority and architect of the Islamic Republic of Iran, grew out of an encounter with the modern understanding of the state and the concept of sovereignty. Khomeini’s political doctrine, called the Absolute Guardianship of the Islamic Jurist, although based on a religious foundation, should be studied as a break with the traditional understanding of political power in Shiism. It will be argued that such a political doctrine can play the same role as the Christian rhetoric of the early modern political thinkers played, pave the way for modernization of Shiite political thought, and prepare the ground for a modern temporal conception of politics.