The past decade has witnessed a significant resurgence of academic and developmental interest in the tropical zones of the world. The task of translating big picture academic institutional vision into practical research can, however, be quite daunting for those at the coalface of implementing such visions, not least because there is no guidance as to where exactly to start. Using James Cook University's tropical vision as a case, this commentary proposes a set of guidelines to assist research teams and organisations to translate the global tropical vision, especially the social and psychological dimensions, into practical research questions.