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1 results

  • A Misconception About the Hardy–Weinberg Law

  • Alan E. Stark
  • Journal:
    Twin Research and Human Genetics / Volume 24 / Issue 3 / June 2021
    Published online by Cambridge University Press:
    22 July 2021, pp. 160-162
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  • The Hardy–Weinberg law of population genetics is usually associated with the notion of random mating of parents. A numerical example for a triallelic autosomal locus shows that an uncountable set of mating combinations can maintain Hardy–Weinberg proportions. Therefore, one cannot infer random mating in a population from the observation of Hardy–Weinberg equilibrium. The mating system which ensures that the genotypic distribution of offspring is the same as that of the parents is specified.