We describe two new species of Heteropterys (Malpighiaceae) endemic to the Atlantic Forest of Espírito Santo State, Brazil. Heteropterys eucalyptifolia and H. follianum belong to the Aptychia informal group, due to their petioles with a pair of glands at the base, sessile pedicels, petals exposed in the enlarging bud, and strongly heteromorphic filaments. Morphological descriptions, illustrations, a distribution map and information on the conservation status of the species are provided.