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Case 14 - Small-Fibre Neuropathy (SFN)
from Peripheral Neuropathies
Jessica E. Hoogendijk, University Medical Center Utrecht, Marianne de Visser, Amsterdam University Medical Center, Pieter A. van Doorn, Erasmus MC, University Medical Center, Rotterdam, Erik H. Niks, Leiden University Medical Center
Book:

Neuromuscular Disease

Published online:

29 November 2024

Print publication:

19 December 2024, pp 110-113
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Summary

A 48-year-old man had complained about the painful soles of his feet for several months. This pain was present constantly but increased on touch and when walking. He was a marathon runner but could no longer train or walk properly because of the pain. He did not report weakness, sensory disturbances, discoloration of his feet, or swelling of his joints. Otherwise, he was healthy. He was not known to have diabetes mellitus or any other chronic disorder, such as sarcoidosis, which can cause a painful neuropathy. There were no cardiovascular or intestinal complaints, and no symptoms of autonomic dysfunction. Symptoms that could suggest malignancy were absent. He did not use any medication, had not been treated with any neurotoxic drug earlier, did not smoke, and drank only very limited amounts of alcohol. There was no family history of neurological disorders.