Studies were conducted in 2001 and 2002 to determine the effect of POST herbicides on the spectral reflectance of corn. POST corn herbicides evaluated included 2,4-D, atrazine, bromoxynil, dicamba + diflufenzopyr, nicosulfuron, and primisulfuron. Multispectral and hyperspectral data were collected and spectral properties were analyzed using SAS procedures and MultiSpec image analysis. Corn treated with POST applications of atrazine and primisulfuron could not be distinguished from nontreated corn regardless of data type or analysis method used. 2,4-D and dicamba + diflufenzopyr were the most readily distinguished from nontreated corn plots using both hyperspectral and multispectral data.