The late Maastrichtian to Late Paleocene seismostratigraphic record of the Roer Valley Graben provides new data on the timing and dynamics of stress changes related to the intra-plate deformation of northwestern Europe. During the deposition of late Maastrichtian to middle Danian limestones, no severe tectonic movements occurred in the southern part of the Roer Valley Graben. Around the late Danian, a known fundamental change in the European intra-plate stress field initiated an increase in subsidence of the southern part of the Roer Valley Graben. Subsidence along the graben border zone enabled relatively thick accumulations of the latest Danian to mid-Selandian siliciclastics in the intra-graben zone. Subsidence was not bounded by large offsets along faults, but rather by flexuring within and along the borders of the Roer Valley Graben. The intensity of these dynamics diminished after the middle Selandian. Most likely due to inherited intra-basinal structural differences, the northern and southern part of the Roer Valley Graben experienced distinctly different late Maastrichtian to Late Paleocene tectonics.