Field studies were conducted to determine the most effective rate of several herbicides applied at various growth stages to control downy brome in conservation fallow programs. Downy brome growth stage affected the efficacy of all herbicides. All herbicides were less effective when application was delayed until the boot stage of downy brome. Fluazifop-P and sethoxydim must be applied prior to tillering to effectively control downy brome. Glyphosate, the commercial mixture of glyphosate plus 2,4-D, paraquat, and HOE-39866 consistently controlled downy brome up to the 3- to 5-tiller stage. Glyphosate at 180 to 200 g ha-1, paraquat at 250 to 300 g ha-1, and the commercial mixture of glyphosate plus 2,4-D at 600 to 660 g ha-1 controlled downy brome 80 to 90%. The effective rates were lower than rates currently registered for downy brome control in western Canada, and thus there is potential for making conservation fallow programs more economical when downy brome is the predominant weed.