Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

1 results

  • 17 - Effect of depression and anxiety on sleep in the elderly

  • from Part 3 - Sleepdisorders in the elderly
  • Edited by S. R. Pandi-Perumal, Jaime M. Monti, Universidad de la República, Uruguay, Andrew A. Monjan, National Institute on Aging, Bethesda, Maryland
  • Book:
    Principles and Practice of Geriatric Sleep Medicine
    Published online:
    04 August 2010
    Print publication:
    26 November 2009, pp 183-194

  • Summary

    The chapter focuses on age-related changes in pathophysiological mechanisms in apneic and normal subjects, and on the potential relevance of the findings to obstructive sleep apnea (OSA). Aging has been reported to be a major factor affecting the risk of OSA. In the extremes of aging, some data suggest a survivor effect, such that apnea prevalence may decrease among elderly patients. The upper airway (UAW) requires stiffness of the soft tissue walls around it and activity of the dilator muscles to maintain patency. Any reduction in UAW cross-sectional area, change in its length, muscle activity, or a combination of these variables, may lead to vulnerability of the UAW to collapse. The term loop gain is used to refer to the intrinsic stability or instability in the ventilatory control system. Once the patient with apnea falls asleep and the cycle of repetitive airway obstruction begins, recurrent hypoxemia and hypercapnia develop.