El Maye is a community located in the municipality of Ixmiquilpan, Hidalgo, in the central region of Mexico. During the late Postclassic period (1350–1521 AD), the Aztecs controlled the area through the establishment of a dual-headed system, one part belonging to the Aztec government and the other to the local government. El Maye was the local government center for the Ixmiquilpan territory under the Aztec domain. The residential units of El Maye archaeological site were constructed in 6 different occupational phases, with the presence of large rooms, stucco floors and walls, offerings, and a variety of ceramics belonging to the late Aztec III ceramic period (1400–1520 AD). The Axis Project of the Mezquital Valley (PEVM-ENAH) and the Accelerator Mass Spectrometry Laboratory (LEMA-UNAM) have undertaken a collaborative study of the El Maye site by performing absolute radiocarbon accelerator mass spectrometry (14C AMS) dating. For a better understanding of the emergence and development of El Maye, a series of AMS 14C dates of charcoal and bone samples recovered from different stratigraphic levels, was performed. This allowed us to locate the occupation of the site between 1320 and 1625 cal AD.