This chapter provides details of the different kinds of vaccines available (live, attenuated, killed, inactivated, recombinant, subunit, mRNA, DNA and vector) for virus infections (e.g. SARS-CoV-2, HAV, HBV, influenzaviruses, JEE, measlesvirus, mumpsvirus, rubellavirus, HPV, rabies, polio, rotavirus, smallpox, mpox, yellow fever virus) in humans. It details the routes of administration and usage (e.g. pre-exposure or post-exposure, childhood, occupational health, travel and for at-risk groups).