While political agenda-setting scholars agree that the news media matter when it comes to agenda setting, surprisingly, there is no consensus on the exact role these media play in the agenda-setting process. In particular, causal interpretations of the media’s role are diverse. This contribution focuses on this ambiguity in the agenda-setting field. First, it outlines the main reasons for the disagreement, both on a theoretical and on an empirical level. Second, it develops a theoretical model that helps to specify what role the news media play under various circumstances. Overall, the paper strongly encourages scholars to reflect more on causal mechanisms in political agenda-setting work, and makes a first attempt at facilitating the interpretation of extant and future findings.