The inheritance of phosphoglucomutase (PGM) was studied electrophoretically in four strains of fig moth, Ephestia cautella. Individual zymograms exhibited one zone of activity with a two-banded pattern in strain A, and one-banded pattern with slow migrating mobility in strains B, C and D. Segregation of banding patterns between parents and progeny in strain A, and chi-square analysis of segregating alleles indicated that the PGM isozymes were regulated by two codominant alleles segregating at a single autosomal locus. No sex linkage was observed in reciprocal crosses. The data also suggest mendelian segregation, and that the PGM isozymes are monomeric in structure. The results of this study indicate that the PGM locus can be a useful marker for studies of E. cautella population dynamics.