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1 results

  • Chapter Ten - The Treatment of Suicide Risk

  • Kees van Heeringen
  • Book:
    The Neuroscience of Suicidal Behavior
    Published online:
    22 May 2019
    Print publication:
    23 August 2018, pp 182-205

  • Summary

    In addition to suicide prediction, neuroscience can be expected to contribute in a unique and substantial way to the treatment of suicide risk. For psychotropic drugs such as lithium and clozapine a specific antisuicidal effect has been demonstrated, independent of effects on associated psychiatric disorders. The results from studies with ketamine are promising as they indicate a rapid and sustained relief of suicidal thoughts. Neurostimulation and neuromodulation provide new approaches to treatment, with a substantial impact on suicide risk. Novel pharmacological compounds targeting the vulnerability to suicidal behavior include drugs that affect the stress-response system and neuroprotective factors.