As part of my interest in the persistence of unproductive debates about the relative importance of nature and nurture, I focus here on the especially problematic relation between nature and the natural. For if the definition of nature is problematic, its semantic relation to ‘natural’ is even more so. I explore some of the problems that arise from slippage between substantive and normative conceptions of ‘natural’ (inviting collateral slippage between is and ought), from the bifurcatory structure of its negation and from changing assumptions about nature’s domain.