This study presents the first extensive investigation of echinoderm distribution in the area of mobile bottoms in the open part of the northern and middle Adriatic Sea. Five hundred and eighteen bottom trawl hauls were performed at 56 predetermined permanent stations along ten transects over different sediment types, at depths of 10 to 430 m. A total of 34 species of Echinodermata were identified (9 from the class Holothuroidea, 12 from the class Asteroidea, 4 from the class Ophiuroidea and 9 from the class Echinoidea). The list of the species, together with data on depth and sediment distribution, and the stations where individual species were found, are presented.