Neuroimaging studies have provided new insights in neural brain circuits and neuroreceptor functions of eating disorders and as a consequence have contributed to a change of the conceptual framework of the pathophysiology and aetiology of eating disorders. Changes in brain structure and metabolism during resting conditions showed several brain alterations in eating-disordered patients. Brain imaging studies using neurotransmitter ligands have offered new opportunities to study neurotransmitter functions and pathways, as well as their relation to pathological behaviour. Neuromediators such as dopamine (DA) and serotonin (5-HT) are believed to be involved in eating disorder pathology. This chapter has summarised findings of neuroimaging research in eating disorders across a wide range of different methods and tools. A promising challenge in the future will be to consider how genetic, developmental and environmental influences shape brain circuit structure and function.