Many of those who dare to raise their voices in defence of human rights in response to abuses committed in connection to mega-projects are being repressed in the Americas. In this context, Indigenous women leaders face multiple forms of violence, including gender-based violence. The prevailing narrative of ‘progress’ and ‘development’ that accompanies mega-projects in the region often stands in stark contrast to their lived experiences, as Indigenous women human rights defenders frequently face silencing practices from companies, authorities and other groups including paramilitary forces. In this article, I contend that Indigenous women leaders have managed to overcome the silence that is being imposed on them. But what are silencing practices? What does gender-based violence mean in this context? How do Indigenous women leaders overcome silencing practices? The article responds to these questions by focusing on the Wayúu Women’s Force mobilization in Colombia and drawing on the emerging ‘braided action’ theoretical framework.