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Secondary oesophageal carcinoma from a breast primary is an infrequent phenomenon. Given the rarity of this presentation, there is a general lack of consensus on management guidelines.
Materials and methods:
Herein, we report a case of a 65-year-old female presented with dysphagia, 14 years post-surgery for breast cancer. She was diagnosed with oesophageal metastases and was treated with combination of systemic chemotherapy, hormonal therapy and local radiotherapy. Our patient tolerated the treatment well and achieved a significant symptomatic improvement post-radiotherapy. We also performed a review of literature on oesophageal metastases from breast primary, aiming to improve the diagnostic accuracy and treatment efficacy in this rare presentation.
Conclusions:
We conclude that patients who present with persistent dysphagia post-breast cancer treatment should undergo an endoscopic ultrasound (EUS)-guided fine-needle biopsy (FNB) to rule out oesophageal metastasis. We suggest systemic chemotherapy with hormonal therapy and radiotherapy for local control as a management of choice in this condition. Even though prognosis is difficult to predict in these patients, this combined modality of treatment seems to achieve better overall survival.
Cholangiocarcinoma (CCA) or klatskin’s tumour involves malignant tumours at the liver hilum’s biliary confluence. Incidence of CCA results in unresectable tumours that require appropriate therapy to improve quality of life. The liver is considered as the most frequent site of tumour recurrence. Promising results of long-term survival have been established with computed tomography-guided high-dose-rate brachytherapy.
Materials and methods:
Intraluminal brachytherapy (ILBT) is performed through the percutaneous transhapatic bile duct drain tube (PTBD). The passage of the brachytherapy guide tube through the bile duct is more complex compared with oesophageal/endobronchial application.
Results/discussion:
It results in a recoiled view of the tube in the abdominal region of the computed tomography (CT) scan. Owing to inherent artefacts induced by metal stents in CT scans, intersected view is possible between the ILBT guide tube and the intra-hepatic drain tube. It would mislead the planner to track wrong passage that could result in fatal error.
Conclusion:
In this case study, we contoured the ILBT guide tube by cross-verifying its position with a digitally reconstructed radiograph (DRR) before catheter tracking. Thus, it ensures precise simulation of source dwell positions, thereby avoiding high-dose delivery to nearby vital organs such as intestines, liver hilum and blood vessels.
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