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20 - Neoplastic disease
from Part II - Neurological diseases
- By John F. Annegers
Albert Hofman, Erasmus Universiteit Rotterdam, Richard Mayeux, Columbia University, New York
Book:

Investigating Neurological Disease

Published online:

29 September 2009

Print publication:

30 August 2001, pp 270-280
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Summary

This chapter highlights the current issues in the epidemiology of brain tumors. It describes the classification of brain tumors in epidemiologic studies, the spatial and temporal occurrence of brain tumors, and the risk factors for brain tumors. Metastatic tumors of the brain may be derived from many primary sites and are of clinical significance because of seizures and other neurologic symptoms. The geographic patterns of brain tumor incidence and mortality rates are relatively stable as is found in many other neurologic diseases such as amyotrophic lateral sclerosis (ALS) and idiopathic epilepsy. Traumatic brain injury has long been considered a risk factor for intracranial neoplasia, especially meningioma. The tumors are then usually demonstrated by magnetic resonance imaging (MRI). The onset of seizure in people aged 35-64 must first be evaluated for benign or malignant brain tumor.