Coapplication of herbicides and insecticides affords growers an opportunity to control multiple pests with one application given that efficacy is not compromised. Trifloxysulfuron was applied at 5.3 g ai/ha both alone and in combination with the insecticides acephate (370 g ai/ha), oxamyl (370 g ai/ha), lambda-cyhalothrin (34 g ai/ha), acetamiprid (45 g ai/ha), thiamethoxam (45 g ai/ha), endosulfan (379 g ai/ha), indoxacarb (123 g ai/ha), emamectin benzoate (11 g ai/ha), methoxyfenozide (67 g ai/ha), spinosad (75 g ai/ha), and pyridalyl (112 g ai/ha) to determine the effects of coapplication on control of some of the more common and/or troublesome broadleaf weeds infesting cotton. In addition, the insecticides acephate, oxamyl, lambda-cyhalothrin, thiamethoxam, and endosulfan, at the rates listed above, were applied either alone or in combination with trifloxysulfuron at 7.9 g/ha to assess the effects of coapplication on thrips control. Control of hemp sesbania (insecticides oxamyl and lambda-cyhalothrin), sicklepod (insecticides methoxyfenozide and pyridalyl), redroot pigweed (insecticides thiamethoxam, methoxyfenozide, spinosad, and pyridalyl), and smooth pigweed, Palmer amaranth, and common lambsquarters (all insecticides) with trifloxysulfuron may be reduced when coapplied with the indicated insecticides for each species. Control of pitted, tall, ivyleaf, and entireleaf morningglory with trifloxysulfuron was not affected by the insecticides evaluated. Coapplication of trifloxysulfuron with the insecticides evaluated also resulted in no negative effects on thrips control.