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immune compromise

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3.7.12 - Antiviral Therapies
from Section 3.7 - Infection and Immunity
- By James McKinlay, Alexander Fletcher
Edited by Ned Gilbert-Kawai, The Royal Liverpool Hospital, Debashish Dutta, Princess Alexandra Hospital NHS Trust, Harlow, Carl Waldmann, Royal Berkshire Hospital, Reading
Book:

Intensive Care Medicine

Published online:

27 July 2023

Print publication:

01 December 2021, pp 285-286
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Summary

Key Learning Points
1. Viral infections are intracellular and more problematic in immunocompromised patients.
2. Apart from antiviral drugs, viral infections are also treated with immunomodulation.
3. Most serious viral infections in the intensive care unit involve the respiratory and/or neurological systems.
4. The mainstay of treatment of serious viral infections is supportive care.
5. Host toxicity from antivirals is likely due to the intracellular nature of infections.