We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure [email protected]
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Since the establishment of in vitro fertilization, it became quickly apparent that approximately half of the couples treated presented with a dysfunctional male gamete. To alleviate this issue, intracytoplasmic sperm injection (ICSI) was introduced to treat men with compromised semen parameters or azoospermia, and more recently high sperm chromatin fragmentation or sperm-linked oocyte activation deficiency. Because of its success, ICSI has been extended for cases with low egg yield, oocyte cryopreservation, and often for preimplantation genetic testing. Due to its versatility and reliability, ICSI has become the most popular ART and will be invaluable for emerging technologies such as in vitro gametogenesis and heritable genome editing. In this chapter, we discuss the development of ICSI, its current applications, and ongoing research that will contribute to the future of reproductive medicine.
Recommend this
Email your librarian or administrator to recommend adding this to your organisation's collection.