The relation between extropy and variational distance is studied in this paper. We determine the distribution which attains the minimum or maximum extropy among these distributions within a given variation distance from any given probability distribution, obtain the tightest upper bound on the difference of extropies of any two probability distributions subject to the variational distance constraint, and establish an analytic formula for the confidence interval of an extropy. Such a study parallels to that of Ho and Yeung [3] concerning entropy. However, the proofs of the main results in this paper are different from those in Ho and Yeung [3]. In fact, our arguments can simplify several proofs in Ho and Yeung [3].