Maize is the single most important food cereal in eastern and southern Africa. Yield levels, however, are among the lowest in the world. Among the major constraints limiting production are the insect pests. Objective assessment of damage and losses caused by these pests are lacking in several countries within the region. This paper discusses some of the methodologies available, and how they can be used to estimate the losses caused by insect pests under different situations. It emphasizes the need for standardization of the methodologies, so that information generated from different countries can be compared. This will promote collective action to combat the pest menace and increase food security.