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A review of the history and pioneers in the study of thirst and drinking is provided, including the debate between dry mouth and systemic theories. The measurement of thirst and drinking is discussed, including whether water has a taste. Consideration is given of the three main phases of components of drinking, namely, its initiation, maintenance, and termination. The chapter ends with the study of brain mechanisms, and in particular the pivotal role of structures of the lamina terminalis.
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