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2 results

  • Psychotic symptoms in mood disorders: evaluation of 159 inpatients

  • A Lenzi, A Rinaldi, I Bianco, C Balestri, D Marazziti
  • Journal:
    European Psychiatry / Volume 11 / Issue 8 / 1996
    Published online by Cambridge University Press:
    16 April 2020, pp. 396-399

  • The authors investigated the historical and clinical variables of 159 inpatients affected by mood disorders in order to identify variables which might differentiate psychotic from non-psychotic forms. The results showed that 32% of the patients had psychotic symptoms. Although no significant difference was detected with regard to the severity of depression, psychotic depressives were younger and had a lower age at onset, as well as a shorter episode length. These features suggest that depression may express itself with or without psychotic symptoms, according to the different individual and, perhaps, biological substrate. Taken together, our findings seem to indicate that psychotic depression should not be considered a separate clinical entity, but a subtype of mood disorders.

  • Correlates of current rapid-cycling bipolar disorder: Results from the Italian multicentric RENDiBi study

  • Massimiliano Buoli, Bruno Mario Cesana, Giuseppe Maina, Andreas Conca, Andrea Fagiolini, Luca Steardo, Jr., A. Carlo Altamura, Bernardo Dell’Osso, on behalf of the ISBD Italian Chapter Epidemiologic Group
  • Journal:
    European Psychiatry / Volume 62 / October 2019
    Published online by Cambridge University Press:
    01 January 2020, pp. 82-89
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  • Background:

    we aimed to compare socio-demographic and clinical differences between patients with versus without current RC in order to detect clinical factors that may favor early diagnosis and personalized treatment.

    Methods:

    A total of 1675 patients (males: n = 714 and females: n = 961; bipolar 1: n = 1042 and bipolar 2: n = 633) from different psychiatric clinics were grouped and compared according to the current presence of RC in terms of socio-demographic and clinical variables. Chi-squared tests for qualitative variables and Student’s t tests for quantitative variables were executed for group comparison, and multivariable logistic regressions were performed, considering the current presence of RC as dependent variable, and socio-demographic/clinical factors as independent variables.

    Results:

    Female gender (male versus female: OR = 0.64, p = 0.04), unidentifiable prevalent polarity (versus depressive polarity: OR = 1.76, p = 0.02; versus manic polarity: OR: 2.86, p < 0.01) and hospitalization in the last year (no versus yes: OR = 0.63, p = 0.02) were found to be associated with RC in the final multivariable regression analysis.

    Conclusions:

    RC in BD seems to be more prevalent in female gender and associated with some unfavorable clinical features, such as an increased risk of hospitalization. These aspects should be taken into account in the management and monitoring of RC versus non-RC patients.