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While there is a physiological basis for the concern about preterm birth with sex in pregnancy, this risk has not been demonstrated in retrospective and prospective studies. In fact, in low-risk patients, sexual activity is typically associated with a decrease in preterm birth. In patients with a history of preterm birth, there is also no evidence that sexual activity increases the risk of preterm birth. Sexually transmitted infections (STIs) should be avoided in pregnancy due to the well-documented increased risk of preterm birth. Notably, sexual cohabitation for 12 months prior to conception (with maternal exposure to sperm) leads to a decrease in preeclampsia and likely to the risk of preterm birth.
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