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1 results

  • 2 - Reproduction and its psychopathology

  • Edited by Regina C. Casper, Stanford University, California
  • Book:
    Women's Health
    Published online:
    08 February 2010
    Print publication:
    13 December 1997, pp 14-35

  • Summary

    Early writers, such as Hippocrates, saw the womb as the seat of emotions and invoked the image of the wandering womb as stirring up emotions in women. Estrogen and progesterone are lipophilic steroid hormones that directly and indirectly affect central nervous system neurons involved in the regulation of mood and cognition. In light of the findings from animal studies, investigators set out with much optimism to identify hormonal changes in blood, and rarely in cerebrospinal fluid (CSF), to establish relationships to the symptoms reported in premenstrual dysphoric disorder (PDD). Several studies have reported that prevalence rates for depressive disorders during pregnancy are similar to those in non-pregnant women. The postpartum blues are experienced by 39-85 percent of women. Classically, the blues begin between 3 to 5 days after delivery with mood lability, sleep disturbances, fatigue, and problems with memory and concentration.