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2 results

  • The prevalence of underweight and obesity in CHD. Response to body mass index and age are associated with ventricular end-diastolic pressure in adults with a Fontan circulation

  • Andriana Anagnostopoulou, Nicholaos G. Eleftherakis, Evangelos Karanasios
  • Journal:
    Cardiology in the Young / Volume 32 / Issue 11 / November 2022
    Published online by Cambridge University Press:
    24 October 2022, pp. 1873-1874
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  • Introduction:

    The aim of the study is to determine the impact of obesity in children with CHD which is severe enough to require invasive catheterisation.

    Methodology:

    This is a retrospective study in a cardiac catheterisation laboratory of a large paediatric hospital. The material consisted of 378 children from 2 to 19 years old who underwent heart catheterisation in the years 2011–2019. Their anthropometric data were collected, and the body mass index was calculated. The BMI centile was then calculated according to the Centers for Diseases Control (CDC). They were classified as overweight (85–95th centile), obese (> 95th centile), normal weight (5th–85 centile), and underweight (< 5th centile).

    Results:

    18.7% of children were underweight, 54.76% were normal weight, 11.64% were overweight, and 14.81% were obese. Overall, 26.45% of the children were overweight. Boys were more likely to have increased body weight than girls, but the difference was not statistically significant. The percentage of increased weight was similar in children with acyanotic CHD as well as heart disease from other causes. On the contrary, children with cyanotic heart disease were more likely to be younger and have a higher percentage of underweight children.

    Conclusions:

    The rates of obesity and overweight in children with CHD depend on the sex, age, and cardiopathy type. In addition, they agree with the findings that have been published in international series studies for children with CHD.

  • An extensively hydrolysed casein-based formula for infants with cows' milk protein allergy: tolerance/hypo-allergenicity and growth catch-up

  • Christophe Dupont, Jeroen Hol, Edward E. S. Nieuwenhuis, the Cow's Milk Allergy Modified by Elimination and Lactobacilli study group
  • Journal:
    British Journal of Nutrition / Volume 113 / Issue 7 / 14 April 2015
    Published online by Cambridge University Press:
    17 March 2015, pp. 1102-1112
    Print publication:
    14 April 2015
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  • Children with cows' milk protein allergy (CMPA) are at risk of insufficient length and weight gain, and the nutritional efficacy of hypo-allergenic formulas should be carefully assessed. In 2008, a trial assessed the impact of probiotic supplementation of an extensively hydrolysed casein-based formula (eHCF) on acquisition of tolerance in 119 infants with CMPA. First analysis of the study results showed that the studied formula allowed improvement of food-related symptoms. The scoring of atopic dermatitis (SCORAD) index was assessed at randomisation and after 6 months of feeding. A post hoc analysis was performed using WHO growth software's nutritional survey module (WHO Anthro version 3.2.2). All infants who were fed the study formula tolerated it well. The SCORAD index significantly improved from randomisation to 6 months of feeding with the study formula. Anthropometric data indicated a significant improvement in the weight-for-age, length-for-age and weight-for-length z scores, as well as in the restoration of normal BMI. The probiotic supplementation did not show any impact on these parameters. The present data showed that this eHCF was clinically tolerated and significantly improved the SCORAD index and growth indices.