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anit-nmdar encephalitis

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Case 67 - A 16-Year-Old G0 Adolescent with Acute Psychosis and 3 cm Ovarian Dermoid Cyst
- By Kim Hoover
Edited by Todd R. Jenkins, University of Alabama, Birmingham, Lisa Keder, Abimola Famuyide, Kimberly S. Gecsi, David Chelmow
Book:

Surgical Gynecology

Published online:

19 November 2021

Print publication:

02 December 2021, pp 203-205
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Summary

The gynecology service is consulted on a 16-year-old gravida 0 admitted to the inpatient psychiatric service to rule out physiologic concerns of acute psychosis. On day 2 of her admission, she had a witnessed grand mal seizure. EEG was performed and demonstrated slow delta waves in the frontal temporal area. An MRI showed no abnormalities and a lumbar puncture revealed lymphocytic pleocytosis and was positive for N-methyl-D-aspartate receptor (NMDAR) antibodies. Her last menstrual period was two weeks ago. She has never been sexually active. She has no past medical or surgical history. Her parents deny concern for alcohol, drug use or ingestion, or tobacco use. She is not taking any medications and has no known drug allergies.