Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

1 results

  • Agitation in patients with dementia: a systematic review of epidemiology and association with severity and course

  • Milena Anatchkova, Anne Brooks, Laura Swett, Ann Hartry, Ruth A. Duffy, Ross A. Baker, Lene Hammer-Helmich, Myrlene Sanon Aigbogun
  • Journal:
    International Psychogeriatrics / Volume 31 / Issue 9 / September 2019
    Published online by Cambridge University Press:
    11 March 2019, pp. 1305-1318
    • Article
      • You have access
      • Open access
    • PDF
    • HTML
    • Export citation
  • Objectives:

    More than 90% of individuals with Alzheimer’s disease (AD) experience behavioral and neuropsychiatric symptoms (NPS), such as agitation. However, little is known regarding the specific burden of agitation for Alzheimer’s patients.

    Design:

    A global systematic literature review was conducted in MEDLINE and Embase for studies of clinical, humanistic, and economic burden of agitation in AD/dementia published from 2006–2016. References of identified papers and related literature reviews were examined. Studies meeting predetermined inclusion criteria for burden of agitation/NPS were summarized.

    Results:

    Eighty papers met the inclusion criteria for burden of agitation in dementia. Wide ranges of agitation prevalence were reported, but few papers provided information on incidence. The association of agitation with AD severity was presented in multiple studies; a few suggested positive association of agitation with mortality.

    Conclusions:

    High prevalence of agitation is consistent with earlier reports, but several gaps in understanding of agitation in AD need further exploration.