Response of ‘Dixie’, ‘Lemondrop’, ‘Multipik’, ‘Superpik’, and ‘Seneca Prolific’ summer squash to halosulfuron PRE or POST at 0.036, 0.053, and 0.072 kg ai/ha, or halosulfuron PRE fb halosulfuron POST at 0.018 fb 0.018, 0.027 fb 0.027, and 0.036 fb 0.036 kg/ha was field evaluated in 1997 and 1998. All halosulfuron treatments and rates reduced the height of cultivars 17–19% at 6 WAP (weeks after planting) and summer-squash injury (chlorosis and necrosis of crop foliage) was 6, 14, and 11% from halosulfuron PRE, POST, and PRE fb POST, respectively. Early summer-squash flowering was reduced 32–82% by halosulfuron, resulting in reduced early yields. Dixie was the cultivar most tolerant to halosulfuron. Early flowering of Dixie was reduced 32–36% compared to 32–82% for the other cultivars. Marketable yield of summer squash was reduced 20–30% by all rates of halosulfuron when averaged over all application timings. Marketable yield of Seneca Prolific, Superpik, Dixie, Multipik, and Lemondrop was reduced 0–17% by halosulfuron PRE. Halosulfuron POST or PRE fb POST reduced marketable yield of all summer-squash cultivars by 25–46%. Thus, summer squash was not tolerant of POST halosulfuron; however, Dixie, Multipik, Seneca Prolific, and Superpik exhibited tolerance to halosulfuron PRE.