This paper presents research and development work on a novel system with a view of developing a navigation system for the guidance of visually impaired pedestrians. The prime aim of the new developed system is to enhance the mobility of visually impaired pedestrians using remote guidance provided by sighted person. However, the system can be used in many other applications. The system implementation is based on the integration of the Global Positioning System (GPS), Geographical Information System (GIS) database and a remote vision facility over the third generation (3G) of mobile networks, providing a technological platform enabling visually impaired pedestrians to be guided remotely by a sighted guide.