The death of Spain’s sickly and heirless King Carlos II in 1700 began the War of Spanish Succession (1701-1714), which brought the French House of Bourbon to the Spanish throne and initiated a series of wars that would shape much of Spain’s eighteenth century. Spanish-British conflict was at the center of the subsequent War of Jenkins’ Ear (1739-1749); and the Seven Years’ War (1756-1763). The desire to control Spanish American markets for consumer goods and for African slaves were at the center of these conflicts, and also shaped the eighteenth-century reform agenda known as the Bourbon reforms, which included measures designed to liberalize trade within the Spanish empire, streamline imperial administration, and transform indigenous Americans into productive workers and consumers of Spanish goods. The chapter also examines the early Age of Revolutions in Spanish America, surveying the indigenous rebellions in Peru that are often referred to as “the Túpac Amaru rebellion,” but were actually three separate, overlapping conflicts. It briefly examines Spain’s contributions to the American Revolutionary War, and concludes by discussing Spain’s involvement in and reaction to the Haitian Revolution.