Methods for efficient variance-based global sensitivity analysis of complex high-dimensional problems are presented and compared. Variance decomposition methods rank inputs according to Sobol indices that can be computationally expensive to evaluate. Main and interaction effect Sobol indices can be computed analytically in the Kennedy and O'Hagan framework with Gaussian processes. These methods use the high-dimensional model representation concept for variance decomposition that presents a unique model representation when inputs are uncorrelated. However, when the inputs are correlated, multiple model representations may be possible leading to ambiguous sensitivity ranking with Sobol indices. In this work, we present the effect of input correlation on sensitivity analysis and discuss the methods presented by Li and Rabitz in the context of Kennedy and O'Hagan's framework with Gaussian processes. Results are demonstrated on simulated and real problems for correlated and uncorrelated inputs and demonstrate the utility of variance decomposition methods for sensitivity analysis.

Many mathematical models involve input parameters, which are not precisely known. Globalsensitivity analysis aims to identify the parameters whose uncertainty has the largestimpact on the variability of a quantity of interest (output of the model). One of thestatistical tools used to quantify the influence of each input variable on the output isthe Sobol sensitivity index. We consider the statistical estimation of this index from afinite sample of model outputs: we present two estimators and state a central limittheorem for each. We show that one of these estimators has an optimal asymptotic variance.We also generalize our results to the case where the true output is not observable, and isreplaced by a noisy version.