This article surveys the evolution of the Catholic Church's official response to same-sex relations over the last two centuries. While the church has not altered its condemnation of same-sex relations, the justifications it offers for this negative judgment have shifted substantially, and they have moved, especially recently, in a direction that makes possible the acceptance of same-sex relations at some future—and perhaps not too-distant—date. This article explores the manualist tradition of the nineteenth and early to mid-twentieth centuries; twentieth-century developments in canon law; and the period of retrenchment and reaction under popes John Paul II and Benedict XVI. Its final section looks at developments under Pope Francis. It closes by considering the way the church's teaching shifted over the course of its history—penance and the forgiveness of sins; anti-Semitism; and the sin against natural-law of taking interest on a loan (usury). It proposes that we might witness the church undergo a similar shift on same-sex relations.