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1 results

  • Responsiveness of Daytime Sleepiness and Fatigue Scales in Myotonic Dystrophy Type 1

  • Luc Laberge, Benjamin Gallais, Julie Auclair, Yves Dauvilliers, Isabelle Côté, Jean Mathieu, Cynthia Gagnon
  • Journal:
    Canadian Journal of Neurological Sciences / Volume 49 / Issue 2 / March 2022
    Published online by Cambridge University Press:
    20 April 2021, pp. 287-290
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  • Daytime sleepiness and fatigue are prominent symptoms of myotonic dystrophy type 1 (DM1) that can be amenable to treatment in the context of randomized controlled trials. No study has yet documented whether self-reported measures of daytime sleepiness and fatigue can detect change over time and the meaning of this change. The aim was to explore indicators of responsiveness to change and interpretability for the Daytime Sleepiness Scale and the Fatigue Severity Scale in 115 DM1 prospectively followed patients. Results suggest that these two self-reported questionnaires are sufficiently sensitive to detect changes beyond expected measurement error over time in this population.