Prognostics and Health Management (PHM) models aim to estimate remaining useful life (RUL) of complex systems, enabling lower maintenance costs and increased availability. A substantial body of work considers the development and testing of new models using the NASA C-MAPSS dataset as a benchmark. In recent work, the use of ensemble methods has been prevalent. This paper proposes two adaptations to one of the best-performing ensemble methods, namely the Convolutional Neural Network – Long Short-Term Memory (CNN-LSTM) network developed by Li et al. (IEEE Access, 2019, 7, pp 75464–75475)). The first adaptation (adaptable time window, or ATW) increases accuracy of RUL estimates, with performance surpassing that of the state of the art, whereas the second (sub-network learning) does not improve performance. The results give greater insight into further development of innovative methods for prognostics, with future work focusing on translating the ATW approach to real-life industrial datasets and leveraging findings towards practical uptake for industrial applications.