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Summary

It has been estimated that 2–3% of all hospital admissions in Australia are medication-related and 50% are preventable (1, 2). A recent review of data from 44 general medical practices in New Zealand demonstrated that 10.8% of patients experienced medication-related harms over a 3-year period. Most were deemed minor; however, one in five harms were moderate or severe and three patients died due to medication harm (3). The almost 2 million Australians that suffer an adverse event from medicines each year (4) are not all due to an adverse drug reactions (ADR), but are also caused by human and systemic medication errors (Table 3.1). Patients claiming a history of drug allergy are a daily occurrence in dental practice, so this chapter includes a description of allergy physiology, various adverse reactions due to drugs, with detail regarding immune-mediated allergic reactions, focussing on Type 1 and 4 reactions. As many claimed allergic reactions by patients are false, how to correctly diagnose and manage actual drug allergies will also be discussed.

Over 3 months, we provided monthly education to internal medicine residents and distributed resources regarding penicillin-allergy history taking. Allergy information in the electronic record was updated more often during the intervention compared to the period before the intervention (16.1% vs 10.9%; P = .02). Education and interdepartmental collaboration have the potential to affect provider behavior.

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3 - Drug allergy versus adverse reactions

Summary

Overcoming challenges to removing inappropriate penicillin allergy labels: A quality improvement report

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2 results

3 - Drug allergy versus adverse reactions

Summary

Overcoming challenges to removing inappropriate penicillin allergy labels: A quality improvement report