This article assesses the major changes in landscape and coastline, which took place in an area adjacent to the northern shore of the inner estuary of the river Humber, in East Yorkshire, UK, from the beginning of the Holocene to the Iron Age. It considers the effect of these changes on material culture as represented by artefact distributions, including flint assemblages and polished stone tools located during field survey. The conclusions presented here derive from a continuing programme of research in this study area and they are placed in the context of the wider Humber region and the North Sea Basin. This article advocates a restoration of balance with regard to geographical determinism – a new pragmatism – accepting that environmental factors have a great importance in determining the nature and location of certain activities in the past, though cannot be used to explain them all.