In this paper we study the existence and the analytic dependence upon domain perturbation of the solutions of a nonlinear nonautonomous transmission problem for the Laplace equation. The problem is defined in a pair of sets consisting of a perforated domain and an inclusion whose shape is determined by a suitable diffeomorphism $\phi$. First we analyse the case in which the inclusion is a fixed domain. Then we will perturb the inclusion and study the arising boundary value problem and the dependence of a specific family of solutions upon the perturbation parameter $\phi$.